Recently I have experimented with vaped THC marijuana flowers which gives me about 5 hours of better-than-Tramadol pain relief from a single puff.  The accompanying high is very mild, like an ounce or two of wine.  This may be working for me due to the THC reaching my blood stream directly without having to go through my liver.  In any case, the pain relief from vaping greatly exceeds the pain relief from taking essentially the same dose orally, even though the oral dose is more intoxicating.  I’m not sure I will be able to completely stop using Tramadol this way, but this seems to offer a hopeful path.  FWIW correctly dosing vaped cannabis is very tricky, best to get some coaching from an experienced vaper otherwise you will initially grossly overdose which will not kill you but may not be to your liking.  I have also tried vaping CBD-only hemp flowers with essentially no results, would be interested to hear from others about their experiences with that…
I have digenerative disc disease/4 bulgin discs was taking 9—10mg hydrocodones a day… i started with 3 drops of 300mg and within 5 mins started feeling better than i have theses last 6 years or so… not only that, the inflamation has decrease substantially, i wake up with energy and have begun to work out again… if im making it seem like a miracle drug… its because it is… so the first week i took 3 drops twice a day… now 3 weeks in… im taking about 5 drops 3 times a day and zero pain pills… for the first time in years i have taken control of my life agin… not depending on doctor scripts/bills etc….

Most drug interactions are in the 3A4 enzyme.  You have no problems there. But candesartan is a strong inhibitor of 2D6.  CBD is an inhibitor of 2D6.  So, yes, they will boast each other.  But you have several options. 1) Use CBD as a boaster, and lower you dose of candesartan, 2) take one in the morning, one in the evening; or 3) Irbesarten is a moderate inhibitor of 2D6.  Losartan, Telmisartan, Valsartan and Eprosartan do not used 2D6.


I have/had ovarian/primary peritoneal cancer. I used thc/cbd oil pills I self made from the start. I am supposedly their “poster child”. I went thru with chemo and surgery. Oh that horror! But when I tried to tell two seperate doctors, the surgeon was all about it, and my oncologist threw a fit and said it was an anecdote. There are more than 100 studies at the NIH govt website.
“Buying from a reputable manufacturer is crucial, because it matters how the plant is cultivated and processed,” Dr. Maroon says. One clue that a company is cutting corners: too low a cost. Good CBD is pricey—a bottle of high-quality capsules is sold in Cohen’s office for $140. But for many, it’s worth the money. Roth spent $60 on her tiny bottle. But when her energy returned the day she started taking CBD, she decided that was a small price to pay.
My mom is late stage dementia.  We have tried coconut oil/black pepper/curcumin combo for years.  Gives only tine bit of help, and is not something that reverses dementia.  Maybe in someone who can score better than a 14 on the mme it could be of help.  But cannabinoid is a different story.  Cannabinoids produce better results in less time.  Can’t say yet that they will reverse anything though.
There is a strong sedative quality to CBD hemp oil, making it a popular remedy for people with insomnia, sleeplessness, interrupted sleep, post-traumatic stress disorder, restless leg disorder, and other night-time issues. Dr. Scott Shannon, Assistant Clinical Professor of Psychiatry at the University of Colorado School of Medicine, USA, published a report in the Permanete Journal, in which he recommended either inhaling a small amount of CBD oil, applying it to one’s chest, or even putting a few drops on one’s pillow to help get a good night’s sleep.
Cannabidiol, or CBD for short, is a natural phyto-cannabinoid (or plant-based chemical compound) found in cannabis plants, including hemp and marijuana. Unlike other cannabinoids — namely tetrahydrocannabinol, or THC — CBD does not produce any psychoactive effects, and will actually counteract these effects to a degree. CBD will induce feelings of sleepiness; for this reason, it can be an effective soporific for people who struggle to fall and/or remain asleep due to insomnia and other sleep disorders.
Insomnia: The anxiety-alleviating and sleep-prolonging qualities of CBD oil make it a good option for many people with insomnia. Those who experience insomnia due to pain or discomfort may also find that using CBD oil alleviates their physical symptoms to a noticeable extent. CBD oil may also promote daytime wakefulness when taken in small amounts; people with insomnia can use it as a pick-me-up if they feel excessively tired due to lack of restful sleep.
When extracting THC from the cannabis plant, it’s not easy to separate the THC from the mixture. This requires skill, expertise, and technology. Some shady brands create DIY CBD oils by using dangerous solvents, and then try to sell their products online. They sell them at extremely low prices, looking to make a quick buck. Before purchasing, always make sure that the CBD oil you are looking at has no psychoactive effects, and makes sure that it has been extracted with CO2 techniques as this ensures that no dangerous chemical solvents were used. And remember that THC is illegal in most states, so you don’t want to get on the wrong side of the law.
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