Hi Diane, how did you go on with the CBD oil please.  If it worked how long before you saw any results.  I’m scared of flaring everything.  Nerve damage across buttocks from a surgeon who found the nerve stuck to the bulge during a laminectomy operation and prised it off.  I haven’t sat for 5 years and getting worse.  A muscle in my buttock is now throbbing constantly and causing pain to the muscle above.  I’ve only started taking it today but the muscle pain is still as painful. Does it take a while for it to work.  Only started on low dose to see what happens.
due to device failures looking at a 3rd surgery.  Has you can imagine the pain, stress and anxiety levels are off the charts. Especially at an otherwise healthy 54 yr women. So i understand from reading posts its best to take it under the tongue. I am taking 1-2 ml a day. I can tell some difference,is your recommended dosage. I am using for pain , stress and sleep. I appreciate your feedback.
Our bodies are thought to produce endocannabinoids by the billions every day. “We always thought the ‘runner’s high’ was due to the release of dopamine and endorphins. But now we know the euphoria is also from an endocannabinoid called anandamide,” its name derived from the Sanskrit word for bliss, says Joseph Maroon, MD, clinical professor and vice chairman of neurosurgery at the University of Pittsburgh Medical Center. We produce these natural chemicals all day, but they fade quickly because enzymes pop up to destroy them. That’s where CBD comes in: By blocking these enzymes, CBD allows the beneficial compounds to linger.
Tinctures are very popular and for a good reason. They offer a unique opportunity for manufacturers to add other robust ingredients, such as coconut oil, terpenes, spearmint, and other natural herbs and essential oils. These additions help mask the pungent taste of natural hemp. The flavor of tinctures is typically more well-received than the pure CBD concentrates, which you’ll find in the next section.
People who experience psychosis may produce too much or even too little cannabinoids (from overactive dopamine receptors). CBD is milder than our internal cannabinoids and helps to re-establish a balance of cannabinoids in the brain. CBD also helps lower inflammation, which is often increased in schizophrenia. THC, on the other hand, is stronger than our internal cannabinoids (anandamide and 2-AG), this way potentially triggering psychosis [46, 48].

That leaves those touting CBD’s effectiveness pointing primarily to research in mice and petri dishes. There, CBD (sometimes combined with small amounts of THC) has shown promise for helping pain, neurological conditions like anxiety and PTSD, and the immune system—and therefore potentially arthritis, diabetes, multiple sclerosis, cancer, and more.
The major problem with CBD bottles on the open market is that in most cases they will contain levels of THC which are higher than the amount legally allowed to sell. This means that in most states (with only a few exceptions such as California, Colorado and Oregon), THC is currently legally available only as Medical Cannabis, and should be sold only by legit dispensaries that have received proper licensing from the state.

Dry Mouth: As is the case with many other hemp- and marijuana-based products, CBD oil often leads to a condition known as dry mouth (or cottonmouth). This is likely due to cannabinoids altering receptors in the lower jaw that trigger salivation. In most cases, mild discomfort and stronger-than-average thirst are the only issues associated with dry mouth.
Transparency: Receptra Naturals’ website has a database where you can look up lab reports for their products. The first time we checked, we got some 404 errors for a couple of the lab reports, but these glitches seem to have been fixed since then. We were able to see third-party lab reports for all their tinctures (though, apparently not for their topicals). 
I’ve been using the green bottle in capsule form to ease my anxiety and insomnia issues. I’ve tried different anxiety medications to no avail (terrible mental side effects) and over the counter sleep aids give me severe nightmares. Not only is my mood stabilized, I’m falling asleep easier and my overall sleep quality has improved greatly. Since the psychoactive effects of traditional marijuana use are not for me, I’m thrilled I’ve found a product that gives me the medicinal benefits I’ve been looking for! 10/10 recommend.
My mom is late stage dementia.  We have tried coconut oil/black pepper/curcumin combo for years.  Gives only tine bit of help, and is not something that reverses dementia.  Maybe in someone who can score better than a 14 on the mme it could be of help.  But cannabinoid is a different story.  Cannabinoids produce better results in less time.  Can’t say yet that they will reverse anything though.
All this talk about THC lands us nicely in the whole “Full Spectrum vs. Pure Isolate” debate. Once you begin shopping for CBD products, you’ll notice a lot of jargon that gets thrown around without much explanation. Now that we’ve introduced THC into the conversation, we can talk about the difference between, and relative benefits of, Full Spectrum CBD and CBD Isolate (and the lesser-known contender: Broad Spectrum).
Stephanie, generally, I have patients take 20 to 150mg a day for sleep +/- anxiety. Start low and go slow. Know the dosages of your product. Usually 2/3 to 3/4 of the daily dose is 1-2 hours before bedtime, and the other portion is upon waking (to improve wakefulness during the day). Other factors such as stress, hormone replacement, other meds & medical conditions, etc. play a role along with individual differences. I own a compounding pharmacy, so we see a lot of unique needs. I can’t give more specific advice in this forum, but there is help!

Most human studies of CBD have been done on people who have seizures, and the FDA recently approved the first CBD-based drug, Epidiolex, for rare forms of epilepsy. Clinical trials for other conditions are promising, but tiny. In one Brazilian study published in 2011 of people with generalized social anxiety disorder, for example, taking a 600-mg dose of CBD (higher than a typical dose from a tincture) lessened discomfort more than a placebo, but only a dozen people were given the pill.
Always striving to source full-spectrum products (rich in other synergetic cannabinoids like CBDa), when Love Hemp launched, it focused on bringing fine organic hemp oils from the EU, particularly from the Czech Republic, into the UK market. For a while, they partnered with Endoca, who allowed them to source organic hemp material from mainland Europe which they would white label under their premium brand in the UK. Later on, when cannabis legislation changed in the USA, they tested Colorado-grown organic hemp from a company called Folium and, because of their guaranteed high quality, they decided this would become the principal source of their CBD hemp oils. All Love Hemp products are THC free (below the 0.2% allowed by UK law), non-addictive, non-toxic and third-party tested for purity.
I wanted to tell people here that CBD has been very effective for my anxiety, and helps with insomnia. For me, it was a cumulative effect, after a week of one dropper of oil, I can sleep very well at night. I feel like I am not polluting my body with commercial pharmaceuticals. I wish everyone here the best, and hope it works for you as well as it has for me.
They have loads of positive customer reviews on their website, including recommendations from a prominent UK/EU CBD user Facebook group. Even though Provacan legally does not advertise their CBD oils as having medicinal effects, one customer (by the name of “Seb”),  noted that he/she use the 6% oil for chronic pain, and after 2 weeks was able to cut their prescription meds by almost 50%.

Nabiximols (Sativex), a multiple sclerosis drug made from a combination of TCH and CBD, is approved in the United Kingdom and Canada to treat MS pain. However, researchers think the CBD in the drug may be contributing more with its anti-inflammatory properties than by acting against the pain. Clinical trials of CBD are necessary to determine whether or not it should be used for pain management.


My mom is late stage dementia.  We have tried coconut oil/black pepper/curcumin combo for years.  Gives only tine bit of help, and is not something that reverses dementia.  Maybe in someone who can score better than a 14 on the mme it could be of help.  But cannabinoid is a different story.  Cannabinoids produce better results in less time.  Can’t say yet that they will reverse anything though.
I take several medications and I need to know if any of my medications will not work with this method of pain reliever. I am getting ready for a shoulder replacement in September. I have Osteoporosis arthritis. I have had both hips replaced and my left shoulder. My sister says that this really works, but I just need to know how it will work with my meds. Thank you
I have had several neurological conditions like Bells Palsy three times, double vision, paralysis of left side of tongue. I have a lot of relief whenever I have pain by taking an inflamattory drug etoshine90 mg. Presently I have started taking Steroids for my facial palsy. The various pains I was having on the left side of neck, below the left ear, dizziness, pain around the head have subsided immidiately after the first dose of prendisolone 60 mg.
Customer Service: We’ve always received fast, informative responses to our queries about products and practices, but there are definitely customers out there who have not. A quick perusal of reviews shows customers who had issues with unaddressed orders. It’s hard to know exactly what the problem is in these situations, but the company’s strict return policy (seven days for unopened products only) probably doesn’t help. It should be noted that the company has a solid base of very satisfied customers as well.
Is the product full spectrum or an isolate? We believe full spectrum CBD oils have greater therapeutic value. Some people talk about the “entourage effect,” or multiple cannabinoids working together. Experts we talk to support the idea of whole-plant therapy. Look for full-spectrum oils. Be careful not to get duped into buying products that use words like “pure” or “potent.” See past the marketing.
People who experience psychosis may produce too much or even too little cannabinoids (from overactive dopamine receptors). CBD is milder than our internal cannabinoids and helps to re-establish a balance of cannabinoids in the brain. CBD also helps lower inflammation, which is often increased in schizophrenia. THC, on the other hand, is stronger than our internal cannabinoids (anandamide and 2-AG), this way potentially triggering psychosis [46, 48].

There are many websites claiming that their CBD oils can cure everything. This is not true! Reputable companies extract their CBD oils from specific strains, and remember that each strain has its own unique CBD/THC ratios. Also, some are Sativa and some are Indica; therefore, the oil extracts may work better on some conditions and some individuals than on others. Always read the fine print, and if a company offers a list of medical conditions the CBD oil treats best, just know that it’s completely bogus.

As mentioned above, CBDPure is a natural oil extracted through cold pressing and CO2 procedures from Cannabis sativa. Specialists have identified over 80 compounds known as cannabinoids. Their research so far showed that CBD is the predominant cannabinoid, accounting for over 40% of the cannabinoids concentration. It is also the most beneficial for human health, at least from the cannabinoids studied so far.
This is the second time Moon Mother Hemp Company has placed among the top five brands on our ranking. The Colorado-based company, which was founded about a year ago, sets the bar very high for quality (including USDA-certified organic hemp) without charging the moon for its products. Their tinctures taste so good, you may be sad you don’t need more.  

I personally take .05MG of Levothyroxine nightly for my hypothyroidism and take CBD oil in the day time and afternoon if needed. Usually a few times a month but I once used it for 2 weeks straight everyday. I didn’t notice any I’ll side effects but I only used enough to get the relaxed feeling. My friend also uses it almost daily and said he heard it was safe for me to use it. It’s all I know my doctor knows I use it also. I figured to be safe I don’t take one next to the other. My prescription gets a good 8+ hours to work as I sleep without any other supplements competing then when I wake I take it as needed. I have combined them at night on a few occasions but don’t like to risk the CBD effecting my thyroid meds.
I’ve just started today with 250mg cbd oil.  I’m starting low to see what happens.  I’ve nerve damage across buttocks from a laminectomy.  I’ve not been able to sit for 5 years. I’ve recently started with a muscle spasm in my left buttock and the muscle above is painful. It is only the first day, also tried a cbd night time tea as well.  Do change in muscle pain so tight on my left hand side.  How long before felt it starting to work please.  I’m trying not to expect changes straightaway.  I also take 1100mg gabapentin and 30mg amitriptyline and I hate both of them – they both can cause muscle tightness affecting the nerve.  Thank you Lyn

Unfortunately, due to strict FDA laws, I am not legally able to say that CBD will help with your husbands specific condition, however I can direct you to some literature to help you better understand what CBD may offer. I have attached links below. As far as strength and dosage goes, tinctures and concentrates are absorbed the fastest since it goes directly into your blood stream; the dosage on these can be measured and controlled. Capsules take a little longer to enter your body since it goes through your digestive tract, these are also measured and controlled. I would recommend reading through our page on dosing as well to get a better understanding.


People who experience psychosis may produce too much or even too little cannabinoids (from overactive dopamine receptors). CBD is milder than our internal cannabinoids and helps to re-establish a balance of cannabinoids in the brain. CBD also helps lower inflammation, which is often increased in schizophrenia. THC, on the other hand, is stronger than our internal cannabinoids (anandamide and 2-AG), this way potentially triggering psychosis [46, 48].
When extracting THC from the cannabis plant, it’s not easy to separate the THC from the mixture. This requires skill, expertise, and technology. Some shady brands create DIY CBD oils by using dangerous solvents, and then try to sell their products online. They sell them at extremely low prices, looking to make a quick buck. Before purchasing, always make sure that the CBD oil you are looking at has no psychoactive effects, and makes sure that it has been extracted with CO2 techniques as this ensures that no dangerous chemical solvents were used. And remember that THC is illegal in most states, so you don’t want to get on the wrong side of the law.
Love Hemp Ltd. is also an ethical promoter of high-quality CBD products who does not engage in dubious advertising techniques. Their product information and labelling are transparent and all products possess third-party certification. They recently partnered with UFC fighters when they saw how CBD had changed their lives. These may not be the ultimate reference models for a health-conscious market, but they’re certainly an interesting testimonial to listen to, as they’re very conscious of their performance and value the importance of recovery after strenuous mental stress and physical exercise. Love Hemp is responsible for breaking ground and shifting the UK public’s perception of cannabis as a source of vegan goodness for people of all ages and creeds. Visit the Love Hemp collection.
Stephanie, generally, I have patients take 20 to 150mg a day for sleep +/- anxiety. Start low and go slow. Know the dosages of your product. Usually 2/3 to 3/4 of the daily dose is 1-2 hours before bedtime, and the other portion is upon waking (to improve wakefulness during the day). Other factors such as stress, hormone replacement, other meds & medical conditions, etc. play a role along with individual differences. I own a compounding pharmacy, so we see a lot of unique needs. I can’t give more specific advice in this forum, but there is help!
They have loads of positive customer reviews on their website, including recommendations from a prominent UK/EU CBD user Facebook group. Even though Provacan legally does not advertise their CBD oils as having medicinal effects, one customer (by the name of “Seb”),  noted that he/she use the 6% oil for chronic pain, and after 2 weeks was able to cut their prescription meds by almost 50%.
Customer Service: We’ve always received fast, informative responses to our queries about products and practices, but there are definitely customers out there who have not. A quick perusal of reviews shows customers who had issues with unaddressed orders. It’s hard to know exactly what the problem is in these situations, but the company’s strict return policy (seven days for unopened products only) probably doesn’t help. It should be noted that the company has a solid base of very satisfied customers as well.
Simply place the CBD Vape Oil in the designated tank (cartridge), turn on the vaporizer, and smoke the CBD vapor. The great thing about taking CBD vaporized is that it works very fast. The bioavailability is very high, which means that a very large part of the CBD being used is absorbed by the body. The CBD gets into the bloodstream very fast through the absorption in the lungs.

Give it some more time… truly. You’ve also increased your dosage pretty quickly in a 3 week period. More is NOT better in CBD land… that’s hard to remember. Give your body time to allow it to work. I’m as skeptical as they come, but my anxiety is far less than 1/2. My overall mood and demeanor is entirely different. My meds are gone, or decreased. Time is the key. Patience is the key. It’s a tricky process, but I’m proof that it works!!


Locsta….I share your pain of degenerative and bulging disk disease, along with fibromyalgia, chronic fatigue and arthritis. Absolutely no energy and chronic pain all day, every day. I’m curious as to what type and brand of the CBD oil you are taking and for how long have you been using it? I’ve been researching CBD oil for months and am quite confused!

A newcomer to our CBD oils ranking, RE: Botanicals is no stranger to hemp. Founded by John Roulac, a long-time hemp advocate and founder of the organic superfoods brand Nutiva, RE: Botanicals is one of the only CBD brands to earn the USDA organic seal. They deserve a shout-out for prioritizing regenerative agriculture, while keeping prices reasonable.   
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